Essential Tremor: What It Is, Causes, Symptoms & Treatment

The ultrastructure of cerebellar Purkinje cells was investigated under TEM. Harmaline significantly altered the ultrastructure of Purkinje cells. The most common ultrastructural findings in harmaline group neurons were nuclear shrinkage, chromatin margination, and RER swelling. The ultrastructure of most Purkinje cells was preserved in the HR, HV, and HRV groups (Fig. 10). In medically refractory cases…